Ecdysteroid receptors in imaginal discs of Drosophila melanogaster.

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Ecdysteroid receptors in imaginal discs of Drosophila melanogaster.

[3H]Ponasterone A (PNA) of high specific activity has been used to identify and begin characterization of ecdysteroid (formerly called ecdysone) receptors in cytoplasmic and nuclear fractions of imaginal discs of Drosophila melanogaster. The equilibrium Kd of the observed macromolecular binding, 3--4 X 10(-9) M PNA, is in good agreement with the minimal concentration required for induction of c...

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Dissection and immunostaining of imaginal discs from Drosophila melanogaster.

A significant portion of post-embryonic development in the fruit fly, Drosophila melanogaster, takes place within a set of sac-like structures called imaginal discs. These discs give rise to a high percentage of adult structures that are found within the adult fly. Here we describe a protocol that has been optimized to recover these discs and prepare them for analysis with antibodies, transcrip...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1978

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.75.12.6039